Types of weight loss injections
Not every injection marketed for weight loss works the same way. These are the main groups our doctors discuss.
- Tirzepatide: weekly GIP and GLP-1 medicine
- Semaglutide: weekly GLP-1 medicine
- Lipotropic injections: vitamin and nutrient support
- Fat-dissolving injections: small local fat pockets
- Body sculpting injections: contour for larger body areas
- Doctor-designed plans combining options over time
Read the detail on Mounjaro and Wegovy, or see the whole obesity clinic programme.
How the options differ
Prescription GLP-1 based medicines are the injections with the strongest evidence for weight management. Tirzepatide acts on GIP and GLP-1 receptors and semaglutide on GLP-1 receptors; both reduce appetite and slow stomach emptying. They are prescription-only, injected once a week, started at a low dose and increased gradually. Clinical trials reported meaningful average weight loss with diet and activity; individual results vary.
Lipotropic injections are blends of B vitamins and nutrients offered to support energy and metabolism, but good evidence that they cause weight loss on their own is limited, so we present them as supportive only. Fat-dissolving injections and body sculpting injections act only where injected, reducing stubborn fat pockets to improve shape rather than lowering overall weight.
Choosing your injection
- Goals and history You discuss whether you want overall weight management or change in a specific area, plus past diets and health.
- Medical check The doctor reviews BMI, body composition, conditions, family history and current medicines.
- Option and plan The doctor recommends a medicine, a local treatment or a combination, and explains side effects and visitor prescription rules.
- Start and monitor Treatment begins if suitable, with follow-up visits or WhatsApp reviews scheduled.
What to expect
Timing and results depend on which type of injection you have and on lifestyle changes.
Are Weight Loss Injections right for you?
Usually a good fit
- Adults wanting medically supervised weight management
- People unsure which injection suits them
- Those near goal weight with stubborn local fat
- Patients able to keep regular follow-up
Talk to your doctor first
- Pregnancy, breastfeeding or planning pregnancy
- Personal or family history of medullary thyroid carcinoma or MEN2
- History of pancreatitis or gallbladder disease
- Diabetes medicines, eating disorders or other conditions: discuss first
Weight loss injections compared
A quick guide to how the main injection types differ.
| Compare | Tirzepatide (Mounjaro) | Semaglutide (Wegovy) | Lipotropic injections | Fat-dissolving injections |
|---|---|---|---|---|
| Works by | GIP and GLP-1 appetite signals | GLP-1 appetite signals | Vitamin and nutrient support | Breaking down fat cells locally |
| Affects | Overall weight | Overall weight | Energy and wellbeing | Shape of one area |
| Prescription | Required | Required | Doctor-advised | Doctor-performed |
| Evidence for weight loss | Strong clinical trial data | Strong clinical trial data | Limited | Not a weight-loss treatment |
Your doctor
At DIORE every treatment is planned and performed by a physician, not delegated. Our five doctors trained at Korea University, Yonsei, Seoul National University Hospital and Dankook.
Chief Director · Medical reviewer
Dr. Lee Gwang-ryeol
- Korea University College of Medicine
- Residency, Korea University Medical Center
- Onda Lifting Key Doctor (DEKA)
- Belotero Revive TTT trainer (Merz) · Rejuran VVIP Club
Honest consultations. Meticulous technique. Results that look like you.
Meet the full medical team.
Aftercare
- Follow your prescribed schedule and do not change doses yourself
- Keep hydrated and eat smaller, balanced meals
- Report severe abdominal pain or persistent vomiting promptly
- Expect swelling and tenderness for days after local injections
- Carry prescriptions and storage advice when travelling
- Keep review appointments or WhatsApp check-ins
For tone and skin firmness alongside injections, ask about Body InMode or skin tightening.
Weight Loss Injections FAQ
Which weight loss injection works best?
For overall weight, prescription GLP-1 based medicines such as tirzepatide and semaglutide have the strongest evidence. Average trial results differ between medicines, but tolerance and individual response vary, so the doctor recommends one after assessing you.
Are weight loss injections safe?
Prescription medicines are generally well studied when prescribed and monitored by a doctor. Common side effects include nausea, vomiting, diarrhoea, constipation and reduced appetite, and some health histories make them unsuitable.
Do lipotropic injections help you lose weight?
Evidence that lipotropic vitamin injections cause weight loss on their own is limited. We offer them only as supportive care within a broader plan.
Can fat-dissolving injections replace weight loss medicine?
No. They reduce small, stubborn fat pockets in one area and do not change overall body weight in a meaningful way.
Can I start weight loss injections during a short trip to Seoul?
It may be possible depending on your health and prescription rules for visitors, which are confirmed at consultation. Message us on WhatsApp before travelling so the doctor can advise.
Do I need to diet while on injections?
Yes. Prescription medicines are designed to be used with a reduced-calorie diet and more physical activity, and lasting habits help maintain results after stopping.
How much do weight loss injections cost?
Cost depends on the type of injection, dose and length of the plan. Message us on WhatsApp for a personalised quote.


